Anaesthesia in craniosynostosis

  • Víctor Hugo González Cárdenas Physician and Surgeon - Anaesthetist - Clinical Epidemiologist, Hospital Infantil Universitario de San José (FUCS), FUCS Instructor, Research Coordinator, Anaesthesia Department and Leader in Anaesthesia Research - Deorum Opus Group, FUCS, Clinical Principal Professor - Universidad de la Sabana, Bogotá, Colombia
  • María Victoria Vanegas Martínez Physician and Surgeon - Cardiovascular and Thoracic Anaesthetist - Specialist in Medical Education, Head of Medical Education, Coordinator of the Operative Unit and the Anaesthesiology Department at Hospital Infantil Universitario de San José, Associate Faculty, FUCS, Colombia
  • María Elvira Rojas Rueda Physician and Surgeon - Anaesthetist, Academic Coordinator of the Anaesthesia Department, Hospital Universitario de San José, Instructor, FUCS, Colombia
  • Nelly Susana Guevara Physician and Surgeon - Anaesthesia Resident, FUCS, Colombia
  • José Rolando Prada Physician and Surgeon - Plastic Surgeon, Reconstructive Surgery Program for Craniofacial Abnormalities, Hospital Infantil Universitario de San José, Instructor FUCS, Colombia
  • Pablo Baquero Physician and Surgeon - Neurosurgeon, Reconstructive Surgery Program for Craniofacial Abnormalities, Hospital Infantil Universitario de San José, Instructor FUCS, Colombia
Keywords: Craniosynostoses, Anesthesia, Tranexamic Acid, Airway Management, Anestesiology


Craniosynostosis is a congenital disorder requiring extensive reconstructive surgery that entails a high probability of severe bleeding, massive transfusion and difficult airway management. Considering that the anaesthetic management for this procedure has special requirements and priority targets, presenting the experience of the anaesthesiology department working under the programme for surgery of craniofacial abnormalities is of the greatest importance.

Objective: Describe the behaviour of anaesthetic variables during the perioperative period inpatients taken to craniosynostosis correction at Hospital Infantil Universitario de San José.

Methods: Retrospective observational cohort study in patients taken to surgery between January 1st 2008 and January 31st 2012. Data were collected from electronic clinical records and anaesthesia records.

Results: The most relevant data were haemorrhage and transfusion. Blood loss was 35.6 cc/kg (SD = 17.4), considered as severe haemorrhage. Patients receiving tranexamic acid did not show lower intra-operative levels of blood loss or packed red blood cell (PRBC) transfusions, shorter mechanical ventilation or ICU (intensive care unit) length of stay. We observed a smaller number of PRBC transfusions in patients in the ICU who received desmopressin.

Conclusions: The high rate of consumption of nutritional supplements in patients about to undergo surgery, possible drug interactions and adverse effects of perioperative consumption of some herbs, should be a warning to the anesthesiologist who performed the pre-anesthetic consultation; is necessary to include this in the interview and take decisions about it. We recommend to request always packing of the products


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How to Cite
González Cárdenas VH, Vanegas Martínez MV, Rojas Rueda ME, Guevara NS, Prada JR, Baquero P. Anaesthesia in craniosynostosis. Colomb. J. Anesthesiol. [Internet]. 2014Jul.1 [cited 2021Dec.5];42(3):199-04. Available from:


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How to Cite
González Cárdenas VH, Vanegas Martínez MV, Rojas Rueda ME, Guevara NS, Prada JR, Baquero P. Anaesthesia in craniosynostosis. Colomb. J. Anesthesiol. [Internet]. 2014Jul.1 [cited 2021Dec.5];42(3):199-04. Available from:
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