Sedation with propofol and remifentanil for real-time endobronchial ultrasound needle aspiration

  • Esther Vila Anesthesia Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
  • Anna Mases Anesthesia Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
  • Enrique Vela Anesthesia Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
  • Luis Molto Anesthesia Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
  • Albert Sanchez-Font Pulmonology Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
  • Víctor Curull Pulmonology Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
  • Lluis Gallart Anesthesia Service, Parc de Salut Mar, Institut de Recerca Hospital del Mar (IMIM), Universitat Autònoma de Barcelona, Spain
Keywords: Endosonography, Propofol, Anesthesia, Bronchoscopy

Abstract

Introduction: Optimal linear endobronchial ultrasound (EBUS) outcomes require sedation to ensure that the patient remains calm, immobile, and does not cough, and so that the bronchoscopist can work comfortably. The choice of anesthesia techniques, on a spectrum ranging from general anesthesia to sedation, is not standardized. The aims of this study were to determine doses, safety and satisfaction for intravenous sedation with propofol and remifentanil, and identify potential predictors of coughing during the procedure, and determine patient and bronchoscopist satisfaction with the procedure.

Patients and methods: The prospective study included patients undergoing EBUS under sedation in a tertiary hospital.

Results: A total of 90 patients underwent EBUS under sedation with remifentanil and propofol, at infusion rates of 0.13 (0.09-0.17) |xgkg-1min-1 and 2.34 (1.5-3.6) mg kg-1 h-1, respectively. Just over four fifths of the patients (81%) coughed at some point during the ultrasound procedure. In 8% of patients the procedure was promptly discontinued due to coughing and desaturation. There were no major complications directly related to sedation. Bronchoscopists and patients rated their satisfaction with the procedure as excellent or good in most cases. There was no statistically significant relationship between the number of coughing episodes during the procedure and any of the following variables: positive cough test, a habitual cough, tobacco dependence, or severity of chronic obstructive pulmonary disease.

Conclusions: Remifentaml and propofol administered by an anesthesiologist enabled spontaneously breathing patients to undergo linear EBUS, although with a high incidence of coughing and particularly desaturation. No predictors for coughing during EBUS were identified.

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How to Cite
1.
Vila E, Mases A, Vela E, Molto L, Sanchez-Font A, Curull V, et al. Sedation with propofol and remifentanil for real-time endobronchial ultrasound needle aspiration. Colomb. J. Anesthesiol. [Internet]. 2013 Apr. 1 [cited 2024 Mar. 29];41(2):120-6. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/877

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Published
2013-04-01
How to Cite
1.
Vila E, Mases A, Vela E, Molto L, Sanchez-Font A, Curull V, et al. Sedation with propofol and remifentanil for real-time endobronchial ultrasound needle aspiration. Colomb. J. Anesthesiol. [Internet]. 2013 Apr. 1 [cited 2024 Mar. 29];41(2):120-6. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/877
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