Surgical site infection in adults undergoing major non-cardiac surgery and its association with anemia, severe bleeding and intraoperative transfusion: A preliminary report from a prospective registry

  • Fredy Ariza Anesthesia and Perioperative Medicine Department, Fundación Valle del Lili. Cali, Colombia. https://orcid.org/0000-0001-5012-5125
  • Darío Alberto Castaño School of Heath Sciences, Universidad ICESI. Cali, Colombia.
  • Julián David Bolaños-Aldana School of Heath Sciences, Universidad ICESI. Cali, Colombia.
  • Manuel Quintana-Díaz Intensive Medicine Service, La Paz University Hospital, Universidad Autónoma de Madrid. Madrid, Spain. https://orcid.org/0000-0003-4852-4148
Keywords: Surgical site infection, Risk factors, Major surgery, Anemia, Major bleeding

Abstract

Introduction

Surgical site infection (SSI) is among the most common healthcare-related infections. Given their greater morbidity and surgical complexity, patients undergoing major surgery are exposed to a high risk of SSI.

Objective

To determine the incidence of SSI in adult patients undergoing major elective non-cardiac surgery, and to identify risk factors associated with its occurrence within the first 30 days after surgery.

Methods

An analytical study was designed on the basis of a prospective institutional registry. Clinical and laboratory variables associated with perioperative management were recorded. An active search was conducted in order to find SSI episodes, renal failure and multiple organ dysfunction during the first 30 days after surgery. Adjusted logistic regression was done to identify potential associations between risk factors and the development of SSI.

Results

Overall, 1501 patients were included. The incidence of SSI during the first 30 days after surgery was 6.72% (95% CI 5.57-8.11). ASA III, abdominal surgery and longer procedures were more frequent in the SSI group. Association with the occurrence of SSI was documented for preoperative hemoglobin levels (adjusted OR 0.79 [95% CI 0.72-0.88], p = 0.04), intraoperative transfusion (adjusted OR 2,47 [95% CI 1.16-5.27], p = 0.02) and major blood loss (adjusted OR 3.80 [95% CI 1.63-8.88], p = 0.04).

Conclusion

Preoperative hemoglobin level, intraoperative transfusion and major bleeding are independent risk factors associated with the occurrence of SSI in adult patients undergoing major elective non-cardiac surgery.

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How to Cite
1.
Ariza F, Castaño DA, Bolaños-Aldana JD, Quintana-Díaz M. Surgical site infection in adults undergoing major non-cardiac surgery and its association with anemia, severe bleeding and intraoperative transfusion: A preliminary report from a prospective registry. Colomb. J. Anesthesiol. [Internet]. 2020Sep.7 [cited 2020Nov.27];48(4). Available from: https://www.revcolanest.com.co/index.php/rca/article/view/925

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Published
2020-09-07
How to Cite
1.
Ariza F, Castaño DA, Bolaños-Aldana JD, Quintana-Díaz M. Surgical site infection in adults undergoing major non-cardiac surgery and its association with anemia, severe bleeding and intraoperative transfusion: A preliminary report from a prospective registry. Colomb. J. Anesthesiol. [Internet]. 2020Sep.7 [cited 2020Nov.27];48(4). Available from: https://www.revcolanest.com.co/index.php/rca/article/view/925
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