Use of matching methods in observational studies with critical patients and renal outcomes. Scoping review

  • Henry Oliveros Rodríguez a. Doctoral Program in Clinical Epidemiology, Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana. Bogotá, Colombia. b. School of Medicine, Universidad de la Sabana. Chía, Colombia.
  • Giancarlo Buitrago Department of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana. Bogotá, Colombia.
  • Paola Castellanos Saavedra School of Medicine, Pontificia Universidad Javeriana. Bogotá, Colombia.
Keywords: Critical illness, Critical care, Renal replacement therapy, Acute kidney injury, Propensity score


Introduction: The use of matching techniques in observational studies has been increasing and is not always used appropriately. Clinical experiments are not always feasible in critical patients with renal outcomes, and observational studies are an important alternative.

Objective: Through a scoping review, determine the available evidence on the use of matching methods in studies involving critically ill patients and assessing renal outcomes.

Methods: Medline, Embase, and Cochrane databases were used to identify articles published between 1992 and 2020 up to week 10, which studied different exposures in the critically ill patient with renal outcomes and used propensity matching methods.

Results: Most publications are cohort studies 94 (94. 9 %), five studies (5. 1 %) were cross-sectional. The main pharmacological intervention was the use of antibiotics in seven studies (7. 1%) and the main risk factor studied was renal injury prior to ICU admission in 10 studies (10. 1%). The balance between the baseline characteristics assessed by standardized means, in only 28 studies (28. 2%). Most studies 95 (96 %) used logistic regression to calculate the propensity index.

Conclusion: Major inconsistencies were observed in the use of methods and in the reporting of findings. A summary is made of the aspects to be considered in the use of the methods and reporting of the findings with the matching by propensity index.


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How to Cite
Oliveros Rodríguez H, Buitrago G, Castellanos Saavedra P. Use of matching methods in observational studies with critical patients and renal outcomes. Scoping review. Colomb. j. anesthesiol. [Internet]. 2020Sep.16 [cited 2020Sep.23];49:e944. Available from:


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How to Cite
Oliveros Rodríguez H, Buitrago G, Castellanos Saavedra P. Use of matching methods in observational studies with critical patients and renal outcomes. Scoping review. Colomb. j. anesthesiol. [Internet]. 2020Sep.16 [cited 2020Sep.23];49:e944. Available from:
Systematic review