@article{Luis E. Chaparro_David S. Grisales_David M. Montes_Juan P. Gutiérrez_Ana M. Valencia R._Ana M. Valencia R._2010, title={The avoidance of neuromuscular paralysis in outpatients requiring endotracheal intubation temporarily increases the incidence of postoperative laryngeal symptoms: quasi-experimental study}, volume={38}, url={https://www.revcolanest.com.co/index.php/rca/article/view/507}, abstractNote={<p><span style="font-family: Verdana; font-size: small;"><strong>Introduction</strong>. Endotracheal intubation without neuromuscular relaxation has become more common, but its impact on surgical units of teaching hospitals is unknown.</span></p> <p><span style="font-family: Verdana; font-size: small;"><strong>Objective</strong>. To assess the impact of avoiding neuromuscular relaxation in terms of incidence of hoarseness and sore throat in ambulatory surgery patients requiring endotracheal intubation in surgical unit of a teaching hospital.</span></p> <p><span style="font-family: Verdana; font-size: small;"><strong>Method</strong>. A quasi-experimental, non-randomized, double-blind study in adult patients undergoing outpatient surgery requiring endotracheal intubation. The non muscle relaxant group received lidocaine (1.5 mg kg<sup>-1</sup>), propofol (1.5 - 2 mg kg<sup>-1</sup>) and remifentanil 4 mcg *kg<sup>-1</sup> and the muscle relaxation group received the same technique and rocuronium 0.3 to 0.6 mg *kg<sup>-1</sup>. The primary outcomes were assessed at days 1, 3 and 14.</span></p> <p><span style="font-family: Verdana; font-size: small;"><strong>Results</strong>. We enrolled 287patients, where 51.7 % received rocuronium. The incidence of hoarseness was significantly higher at 24 hours in the nonrelaxant group (26 % vs. 15 %, p value: 0.016) being not significant after 72 hours of follow up (0.6 % vs. 0 %; p: 0.37). We found no differences in the incidence of sore throat between the groups. All the study patients were asymptomatic at one week.</span></p> <p><span style="font-family: Verdana; font-size: small;"><strong>Conclusions</strong>. Avoidance of neuromuscular relaxation is associated with a transient (First 24 hours) increase in hoarseness after ambulatory surgery, but no difference in sore throat. We found no differences in the incidence of laryngeal symptoms after 72 hours. The addition of muscle relaxant to reduce the incidence of hoarseness can be justified.</span></p> <p><span style="font-family: Verdana; font-size: small;"><strong>Keywords</strong>: Intratracheal intubation, general anesthesia, adverse effects, methods, postoperative complications <em>(Source: MeSH, NLM)</em>.</span></p>}, number={3}, journal={Colombian Journal of Anesthesiology}, author={Luis E. Chaparro and David S. Grisales and David M. Montes and Juan P. Gutiérrez and Ana M. Valencia R. and Ana M. Valencia R.}, year={2010}, month={Jul.}, pages={335–346} }