Anaesthetic Management of a Haemophiliac patient with Thrombophilia
Abstract
Haemophiliac patient are known to have increased mortality and morbidity in the past due to previous non existence of practice of blood banking. Mainly morbidity increased due to the complications arises such as recurrent bleeding episodes, painful haemarthroses and permanent disability secondary to ankylosed joints. This case enlightens the role and impact of undetected changes in Hemophilia A patient with Buerger's disease, highlighting the importance of vigilance on the part of the anesthesiologist, who must ensure the adequacy of hemostatic monitoring in these patients. The clinical presentation of Haemophilia A disease with Buerger's disease is a rare entity and can be challangeable for practicing anaesthesiology.
References
2. Trifiletti A, Scamardi R, Bagnato GF, Gaudio A. Hemostatic changes in vasculitides. Thromb Res. 2009; 124:252-5.
3. Mannucci PM, Tuddenham EG. The hemophilias-from royal genes to gene therapy. N Engl J Med 2001; 344: 1782-84
4. Hus et al. (December, 2008). Assessment of Plasma Prothrombotic Factors in Patients with Buerger's Disease. Unpublished paper presented at 50th Annual ASH Meeting & Exposition, San Francisco, CA.
5. DiMichele D, Neufeld EJ. Hemophilia. A new approach to an old disease. Hematol Oncol Clin North Am 1998; 12: 1315-44.
6. Cahill MR, Colvin BT. Haemophilia. Postgrad Med J 1997;73: 201-06
7. William ED, D David Glass. Haematological diseases. In: Katz, Benumof, kadis. Anesthesia and uncommon diseases. Philadelphia 1990; 378-436.
8. Fudeta H, Hashimoto YK, Mori K. Anesthesia in patients with hemophilia A and B. Jpn J Anesth 1976; 25 : 718.
9. Brinkhaus KM. The hemophilias. Chapel Hill, University of North Carolina Press.1964; 69.
10. de Gruchy's. Clinical haematology in medical practice, Coagulation disorders. In: Frank Firkin, Colin Chesterman, David Pennington, Bryan Rush. 5th Ed. New Delhi: Oxford University Press. 1993; 40636.
11. Hathaway WE, Mahasondana C, Clarke S, Humbertr JR. Paradoxical bleeding in intensively transfused hemophiliacs. Transfusion 1973; 13: 6-12.
12. Roberts HR. Hemophiliacs with inhibitors: Therapeutic considerations. N Engl J Med 1981; 305:757.
13. Curran JW, Lawrence DN, Jaffe H, et al. Acquired immunodeficiency syndrome (AIDS) associated with transfusions. N Engl J Med 1984; 69: 310.
14. Abramovitz S, Beilin Y. Thrombocytopenia, low molecular weight heparin, and obstetric anesthesia. Anesth Clin N Am 2003; 21: 99-109.
15. Simon E, Roux C, More J. Drug combinations in the treatment of pain in hemophiliacs. Bibl Haematologica 1966; 26: 78.
Downloads
Altmetric
Article metrics | |
---|---|
Abstract views | |
Galley vies | |
PDF Views | |
HTML views | |
Other views |