New perspectives in the treatment of obstructive sleep apnea-hypopnea syndrome

  • Edgar Cortés-Reyes Department of Human Body Movement, Institute of Clinical Research, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá, D.C., Colombia
  • Katherine Parrado-Bermúdez Department of Human Body Movement, Institute of Clinical Research, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá, D.C., Colombia
  • Franklin Escobar-Córdoba a. Department of Psychiatry, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá, D.C., Colombia. b. Sueño Vigilia Colombiana Foundation, Bogotá, D.C., Colombia
Keywords: Sleep apnea syndromes, Obesity, Comorbidity, Therapeutics, Airway obstruction


lntroduction: Obstructive sleep apnea-hypopnea syndrome (OSA) is an increasingly prevalent Received 2 February 2016 disorder in the population, which seriously compromises the quality of life of sufferers. Although continuous positive airway pressure remains the most commonly used treatment modality, its poor adhesion and relative failure have provoked several studies seeking to develop more convenient and effective alternatives for treating this condition.

Objective: To review the most effective, recent and innovative strategies that scientific evidence suggests for the treatment of OSA from anatomical and physiological mechanisms involved.

Materials and methods: A literature review was performed from items taken from PubMed, ScienceDirect, Springer, LILACS and PEDro databases, published between 2005 and 2015 in English.

Results: OSA is an intermittent and repetitive obstruction of the upper airway during sleep, caused mainly by an imbalance in respiratory muscle synergy. For treatment, the scientific literature has recently described methods such as oral devices, oral and nasal pressure therapies, Pillar, the Night Shift, bariatric surgery and stimulation of the hypoglossal nerve.

Conclusions: Although a fully effective treatment is not yet available, acombination of strategies from an interdisciplinary perspective can enhance the quality of life of patients. It is expected that in the coming years, the scientific and technological advances will allow for the implementation of a treatment protocol that is able to directly address the etiological processes to reduce their prevalence.


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How to Cite
Cortés-Reyes E, Parrado-Bermúdez K, Escobar-Córdoba F. New perspectives in the treatment of obstructive sleep apnea-hypopnea syndrome. Colomb. J. Anesthesiol. [Internet]. 2017 Jan. 1 [cited 2024 May 30];45(1):62-71. Available from:


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How to Cite
Cortés-Reyes E, Parrado-Bermúdez K, Escobar-Córdoba F. New perspectives in the treatment of obstructive sleep apnea-hypopnea syndrome. Colomb. J. Anesthesiol. [Internet]. 2017 Jan. 1 [cited 2024 May 30];45(1):62-71. Available from:
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