Case report and literature review: Hyperpyrexia as side effect following the administration of sub-lingual misoprostol in the management of post-partum hemorrhage
Keywords:
Fever, Misoprostol, Hyperpyrexia, Postpartum haemorrhage.
Abstract
This is a patient with post-partum hemorrhage (PPH), secondary to uterine atony managed with sub-lingual misoprostol 1000μg . Hyperpyrexia resulting from the route of administration of the drug and the clinical presentation of the condition, give rise to diagnostic difficulties and special interventions during the management process. A literature review on misoprostol, its pharmacological profile and side effects concluded that sub-lingual misoprostol results in a maximum concentration and is associated with the highest incidence of side effects as compared to other routes of administration
References
1. OMS. Maternal Mortality in 2005: estimates developed by WHO, Unicef, UNFPA, and the World Bank. WHO Publications; 2007.
2. República de Colombia, Ministerio de la Protección Social - Organización Panamericana de la Salud. Situación de salud en Colombia. Indicadores básicos de salud 2007. Disponible en: http://www.minproteccionsocial.gov.co/VBeContent/NewsDetail.asp?ID=15895&IDCompany=3 consultado 4 Ago 2011 .
3. Benagiano G, Thomas B. Saving mothers' lives: the FIGO Save the Mothers Initiative. Int J Gynaecol Obstet. 2003;80:198-203.
4. ACOG. Postpartum hemorrhage. Obstet Gynecol. 2006;108:1039-47.
5. Durocher J, Bynum J, León W, Barrera G, Winikoff B. High fever following postpartum administration of sublingual misoprostol. BJOG. Disponible en: http://dx.doi.org/10.1111/j.1471-528.2010.02564.x consultado 4 Ago 2011 .
6. Tang OS, Gemzell-Danielsson K. Misoprostol: Pharmakocinetic profiles, effects on the uterus and side-effects. Int J Gynaecol Obstet. 2007;99:S160-7.
2. República de Colombia, Ministerio de la Protección Social - Organización Panamericana de la Salud. Situación de salud en Colombia. Indicadores básicos de salud 2007. Disponible en: http://www.minproteccionsocial.gov.co/VBeContent/NewsDetail.asp?ID=15895&IDCompany=3 consultado 4 Ago 2011 .
3. Benagiano G, Thomas B. Saving mothers' lives: the FIGO Save the Mothers Initiative. Int J Gynaecol Obstet. 2003;80:198-203.
4. ACOG. Postpartum hemorrhage. Obstet Gynecol. 2006;108:1039-47.
5. Durocher J, Bynum J, León W, Barrera G, Winikoff B. High fever following postpartum administration of sublingual misoprostol. BJOG. Disponible en: http://dx.doi.org/10.1111/j.1471-528.2010.02564.x consultado 4 Ago 2011 .
6. Tang OS, Gemzell-Danielsson K. Misoprostol: Pharmakocinetic profiles, effects on the uterus and side-effects. Int J Gynaecol Obstet. 2007;99:S160-7.
How to Cite
1.
Martínez Pacheco FH, Zambrano Benítez CP. Case report and literature review: Hyperpyrexia as side effect following the administration of sub-lingual misoprostol in the management of post-partum hemorrhage. Colomb. J. Anesthesiol. [Internet]. 2013 Jan. 1 [cited 2024 May 5];41(1):65-8. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/563
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Published
2013-01-01
How to Cite
1.
Martínez Pacheco FH, Zambrano Benítez CP. Case report and literature review: Hyperpyrexia as side effect following the administration of sub-lingual misoprostol in the management of post-partum hemorrhage. Colomb. J. Anesthesiol. [Internet]. 2013 Jan. 1 [cited 2024 May 5];41(1):65-8. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/563
Issue
Section
Case Report / Case Series
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