Thromboelastography: Overall Evaluation of Coagulation. Perioperative Applications
Keywords:
Thrombelastography, blood coagulation, perioperative period, diagnosis.
Abstract
Thromboelastography is a relatively new diagnostic method designed for a global evaluation of coagulation. This method has rapidly evolved and is frequently used in the clinic for the evaluation of coagulopathies and as guide for intervention; furthermore, its routine application on a daily basis reduces the need for transfusion of hemoderivatives, and consequently lessens the costs and complications thereof. This case report of patients from the San Ignacio University Hospital, describes infrequent clinical situations in which the use of thromboelastography provides an excellent diagnostic aid and treatment guide during the perioperative period.
References
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2. Reikvam H, Steien E, Hauge B, et al. Thrombelastography. Transfus Apher Sci. 2009; 40:119-23.
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7. Dai Y, Lee A, Critchley LA, et al. Does thromboelastography predict postoperative thromboembolic events? A systematic review of the literature. Anesth Analg. 2009;108:734-42.
8. Park MS, Martini WZ, Dubick MA, et al. Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time. J Trauma. 2009;67:266,75; discussion 275-6.
9. Chen A, Teruya J. Global hemostasis testing thromboelastography: old technology, new applications. Clin Lab Med. 2009;29:391-407.
10. Schreiber MA, Differding J, Thorborg P, et al. Hypercoagulability is most prevalent early after injury and in female patients. J Trauma. 2005;58:475,80; discussion 480-1.
11. Sharma P, Saxena R. A novel thromboelastographic score to identify overt disseminated intravascular coagulation resulting in a hypocoagulable state. Am J Clin Pathol. 2010;134:97-102.
12. Wilson D, Cooke DA, McNally MA, et al. Changes in coagulability as measured by thrombelastography following surgery for proximal femoral fracture. Injury. 2001;32:765-70.
13. McCrath DJ, Cerboni E, Frumento RJ, et al. Thromboelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction. Anesth Analg. 2005;100:1576-83.
14. Zufferey P, Merquiol F, Laporte S, et al. Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery? Anesthesiology. 2006;105:1034-46.
15. Benoni G, Fredin H, Knebel R, et al. Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations. Acta Orthop Scand. 2001;72:442-8.
16. Ickx BE, van der Linden PJ, Melot C, et al. Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation. Transfusion. 2006;46:595-605.
17. Gallimore MJ, Harris SL, Tappenden KA, et al. Urokinase induced fibrinolysis in thromboelastography: a model for studying fibrinolysis and coagulation in whole blood. J Thromb Haemost. 2005;3:2506-13.
18. Zmuda K, Neofotistos D, Ts'ao CH. Effects of unfractionated heparin, low-molecular-weight heparin, and heparinoid on thromboelastographic assay of blood coagulation. Am J Clin Pathol. 2000;113:725-31.
19. Coppell JA, Thalheimer U, Zambruni A, et al. The effects of unfractionated heparin, low molecular weight heparin and danaparoid on the thromboelastogram (TEG): an in-vitro comparison of standard and heparinase-modified TEGs with conventional coagulation assays. Blood Coagul Fibrinolysis. 2006;17:97-104.
20. Simons R, Mallett SV. Use of thromboelastography to demonstrate persistent anticoagulation after stopping enoxaparin. Anaesthesia. 2007;62:1175-8.
21. Van PY, Cho SD, Underwood SJ, et al. Thrombelastography versus AntiFactor Xa levels in the assessment of prophylactic-dose enoxaparin in critically ill patients. J Trauma. 2009;66:1509,15; discussion 1515-7.
22. Klein SM, Slaughter TF, Vail PT, et al. Thromboelastography as a perioperative measure of anticoagulation resulting from low molecular weight heparin: a comparison with anti-Xa concentrations. Anesth Analg. 2000;91:1091-5.
23. Modi HN, Suh SW, Hong JY, et al. Intraoperative blood loss during different stages of scoliosis surgery: A prospective study. Scoliosis. 2010;5:16.
24. Coppola A, Di Minno G. Desmopressin in inherited disorders of platelet function. Haemophilia. 2008;14 Suppl 1:31-9.
25. Theroux MC, Corddry DH, Tietz AE, et al. A study of desmopressin and blood loss during spinal fusion for neuromuscular scoliosis: a randomized, controlled, double-blinded study. Anesthesiology. 1997;87: 260-7.
26. Stevens W, Koene H, Zwaginga JJ, et al. Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights. Neth J Med. 2006;64:356-63.
27. Webert KE, Mittal R, Sigouin C, et al. A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura. Blood. 2003;102: 4306-11.
2. Reikvam H, Steien E, Hauge B, et al. Thrombelastography. Transfus Apher Sci. 2009; 40:119-23.
3. Ak K, Isbir CS, Tetik S, et al. Thromboelastographybased transfusion algorithm reduces blood product use after elective CABG: a prospective randomized study. J Card Surg. 2009;24:404-10.
4. Wasowicz M, McCluskey SA, Wijeysundera DN, et al. The incremental value of thrombelastography for prediction of excessive blood loss after cardiac surgery: an observational study. Anesth Analg. 2010;111: 331-8.
5. American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology. 2006;105:198-208.
6. Luddington RJ. Thrombelastography/thromboelastometry. Clin Lab Haematol. 2005;27:81-90.
7. Dai Y, Lee A, Critchley LA, et al. Does thromboelastography predict postoperative thromboembolic events? A systematic review of the literature. Anesth Analg. 2009;108:734-42.
8. Park MS, Martini WZ, Dubick MA, et al. Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time. J Trauma. 2009;67:266,75; discussion 275-6.
9. Chen A, Teruya J. Global hemostasis testing thromboelastography: old technology, new applications. Clin Lab Med. 2009;29:391-407.
10. Schreiber MA, Differding J, Thorborg P, et al. Hypercoagulability is most prevalent early after injury and in female patients. J Trauma. 2005;58:475,80; discussion 480-1.
11. Sharma P, Saxena R. A novel thromboelastographic score to identify overt disseminated intravascular coagulation resulting in a hypocoagulable state. Am J Clin Pathol. 2010;134:97-102.
12. Wilson D, Cooke DA, McNally MA, et al. Changes in coagulability as measured by thrombelastography following surgery for proximal femoral fracture. Injury. 2001;32:765-70.
13. McCrath DJ, Cerboni E, Frumento RJ, et al. Thromboelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction. Anesth Analg. 2005;100:1576-83.
14. Zufferey P, Merquiol F, Laporte S, et al. Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery? Anesthesiology. 2006;105:1034-46.
15. Benoni G, Fredin H, Knebel R, et al. Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations. Acta Orthop Scand. 2001;72:442-8.
16. Ickx BE, van der Linden PJ, Melot C, et al. Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation. Transfusion. 2006;46:595-605.
17. Gallimore MJ, Harris SL, Tappenden KA, et al. Urokinase induced fibrinolysis in thromboelastography: a model for studying fibrinolysis and coagulation in whole blood. J Thromb Haemost. 2005;3:2506-13.
18. Zmuda K, Neofotistos D, Ts'ao CH. Effects of unfractionated heparin, low-molecular-weight heparin, and heparinoid on thromboelastographic assay of blood coagulation. Am J Clin Pathol. 2000;113:725-31.
19. Coppell JA, Thalheimer U, Zambruni A, et al. The effects of unfractionated heparin, low molecular weight heparin and danaparoid on the thromboelastogram (TEG): an in-vitro comparison of standard and heparinase-modified TEGs with conventional coagulation assays. Blood Coagul Fibrinolysis. 2006;17:97-104.
20. Simons R, Mallett SV. Use of thromboelastography to demonstrate persistent anticoagulation after stopping enoxaparin. Anaesthesia. 2007;62:1175-8.
21. Van PY, Cho SD, Underwood SJ, et al. Thrombelastography versus AntiFactor Xa levels in the assessment of prophylactic-dose enoxaparin in critically ill patients. J Trauma. 2009;66:1509,15; discussion 1515-7.
22. Klein SM, Slaughter TF, Vail PT, et al. Thromboelastography as a perioperative measure of anticoagulation resulting from low molecular weight heparin: a comparison with anti-Xa concentrations. Anesth Analg. 2000;91:1091-5.
23. Modi HN, Suh SW, Hong JY, et al. Intraoperative blood loss during different stages of scoliosis surgery: A prospective study. Scoliosis. 2010;5:16.
24. Coppola A, Di Minno G. Desmopressin in inherited disorders of platelet function. Haemophilia. 2008;14 Suppl 1:31-9.
25. Theroux MC, Corddry DH, Tietz AE, et al. A study of desmopressin and blood loss during spinal fusion for neuromuscular scoliosis: a randomized, controlled, double-blinded study. Anesthesiology. 1997;87: 260-7.
26. Stevens W, Koene H, Zwaginga JJ, et al. Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights. Neth J Med. 2006;64:356-63.
27. Webert KE, Mittal R, Sigouin C, et al. A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura. Blood. 2003;102: 4306-11.
How to Cite
1.
Gempeler R. FE, Perea B AH, Diaz L. Thromboelastography: Overall Evaluation of Coagulation. Perioperative Applications. Colomb. J. Anesthesiol. [Internet]. 2011 Jul. 1 [cited 2024 Apr. 29];39(3):410-23. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/847
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Published
2011-07-01
How to Cite
1.
Gempeler R. FE, Perea B AH, Diaz L. Thromboelastography: Overall Evaluation of Coagulation. Perioperative Applications. Colomb. J. Anesthesiol. [Internet]. 2011 Jul. 1 [cited 2024 Apr. 29];39(3):410-23. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/847
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Case Report / Case Series
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