The Use of Dexmedetomidine (DXM) for Implanting a Cardiac Resynchronization Device: Is it Really Safe?
Keywords:
Dexmedetomidine, biological clocks, amiodarone, safety measures.
Abstract
Dexmedetomidine (DXM) is a selective 2-adrenoreceptor agonist acting over both the central and peripheral nervous system. Since it became available for medical application, DXM has been satisfactorily used for a broad spectrum of anesthetic procedures, ranging from sedation to interventions under general anesthesia. Its key advantages include its hemodynamic stability and minimal respiratory depression. This article provides a description of a successful cardiac resynchronization therapy implanting a biventricular pacemaker in a hemodynamically unstable patient under DXM and low-dose midazolam sedation.
References
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2. Bekker AY, Basile J, Gold M, et al. Dexmedetomidine for Awake Carotid Endarterectomy: efficacy, hemodynamic profile, and side effects. J Neurosurg Anesthesiol. 2004;16:126-35.
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7. Gurbet A, Basagan-Mogol E, Turker G, et al. Intraoperative infusion of dexmedetomidine reduces perioperative analgesic requirements. Can J Anesth. 2006;53:646-52.
8. Talke PO, Caldwell JE, Richardson CA, et al. The effects of dexmedetomidine on neuromuscular blockade in human volunteers. Anesth Analg. 1999;88:633-9.
9. Martin E, Ramsay G, Mantz J, et al: The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. J Intensive Care Med. 2003;18:29-41.
10. Aantaa R, Jalonen J. Perioperative use of alpha2- adrenoceptor agonists and the cardiac patient. Eur J Anaesthesiol. 2006;23:361-72.
11. Ho AM, Chen S, Karmakar MK. Central apnoea after balanced general anaesthesia that included dexmedetomidine. Br J Anaesth. 2005;95:773-5.
12. Ingersoll-Weng E, Manecke G, Thistlethwaite P. Dexmedetomidine and cardiac arrest. Anesthesiology. 2004;100:738-9.
13. Shah AN, Koneru J, Nicoara A, et al. Dexmedetomidine related cardiac arrest in a patient with permanent pacemaker; a cautionary tale. Pacing Clin Electrophysiol. 2007;30:1158-60.
2. Bekker AY, Basile J, Gold M, et al. Dexmedetomidine for Awake Carotid Endarterectomy: efficacy, hemodynamic profile, and side effects. J Neurosurg Anesthesiol. 2004;16:126-35.
3. Bhana N, Goa K, McClellan KJ. Dexmedetomidine. Drugs. 2000;59:263-8.
4. Mato M, Pérez A, Otero J, et al. Dexmedetomidina, un fármaco prometedor. Rev Esp Anestesiol Reanim. 2002;49:407-20.
5. Rozet I. Anesthesia for functional neurosurgery: the role of dexmedetomidine. Curr Opin Anaesthesiol. 2008;21:537-43.
6. Wagner DS, Brummett CM. Dexmedetomidine: as safe as safe can be. Seminars in Anesthesia Perioperative Medicine and Pain. 2006;25:77-83.
7. Gurbet A, Basagan-Mogol E, Turker G, et al. Intraoperative infusion of dexmedetomidine reduces perioperative analgesic requirements. Can J Anesth. 2006;53:646-52.
8. Talke PO, Caldwell JE, Richardson CA, et al. The effects of dexmedetomidine on neuromuscular blockade in human volunteers. Anesth Analg. 1999;88:633-9.
9. Martin E, Ramsay G, Mantz J, et al: The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. J Intensive Care Med. 2003;18:29-41.
10. Aantaa R, Jalonen J. Perioperative use of alpha2- adrenoceptor agonists and the cardiac patient. Eur J Anaesthesiol. 2006;23:361-72.
11. Ho AM, Chen S, Karmakar MK. Central apnoea after balanced general anaesthesia that included dexmedetomidine. Br J Anaesth. 2005;95:773-5.
12. Ingersoll-Weng E, Manecke G, Thistlethwaite P. Dexmedetomidine and cardiac arrest. Anesthesiology. 2004;100:738-9.
13. Shah AN, Koneru J, Nicoara A, et al. Dexmedetomidine related cardiac arrest in a patient with permanent pacemaker; a cautionary tale. Pacing Clin Electrophysiol. 2007;30:1158-60.
How to Cite
1.
Botero Posada LF, Arias Jiménez JM, Vasseur Arboleda JP. The Use of Dexmedetomidine (DXM) for Implanting a Cardiac Resynchronization Device: Is it Really Safe?. Colomb. J. Anesthesiol. [Internet]. 2011 Jul. 1 [cited 2024 Apr. 29];39(3):425-31. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/848
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Published
2011-07-01
How to Cite
1.
Botero Posada LF, Arias Jiménez JM, Vasseur Arboleda JP. The Use of Dexmedetomidine (DXM) for Implanting a Cardiac Resynchronization Device: Is it Really Safe?. Colomb. J. Anesthesiol. [Internet]. 2011 Jul. 1 [cited 2024 Apr. 29];39(3):425-31. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/848
Issue
Section
Case Report / Case Series
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