Efficacy of cannabinoids in fibromyalgia: a literature review

Keywords: Fibromyalgia, Medical marijuana, Cannabinoids, Dronabinol, Tetrahydrocannabinol, Cannabidiol


Fibromyalgia is a chronic disease of unclear etiology, involving a neural oversensitization and impaired pain modulation, in addition to a clinical deficiency of the endocannabinoid system. Fibromyalgia is associated with a number of somatic and psychological disorders and hence multiple pharmacological approaches have been used, including   opioids, antidepressants, antiepileptics, and more recently medical cannabis. This narrative review comprises a review of the current literature on the efficacy of   cannabinoids in fibromyalgia. The studies describe a possible influence of cannabis on pain control in patients with fibromyalgia, with positive effects on quality of life and sleep. The use of cannabis seems to be beneficial in patients with fibromyalgia; however, more robust studies are still needed to establish is actual efficacy in pain management, quality of life and improvement of associated symptoms.


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How to Cite
Mayorga Anaya HJ, Torres Ortiz MP, Flórez Valencia DH, Gomezese Ribero OF. Efficacy of cannabinoids in fibromyalgia: a literature review. Colomb. J. Anesthesiol. [Internet]. 2021 Mar. 26 [cited 2024 Feb. 28];49(4). Available from: https://www.revcolanest.com.co/index.php/rca/article/view/980


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How to Cite
Mayorga Anaya HJ, Torres Ortiz MP, Flórez Valencia DH, Gomezese Ribero OF. Efficacy of cannabinoids in fibromyalgia: a literature review. Colomb. J. Anesthesiol. [Internet]. 2021 Mar. 26 [cited 2024 Feb. 28];49(4). Available from: https://www.revcolanest.com.co/index.php/rca/article/view/980
Narrative review


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