Dantrolene reconstitution: description of a simulation model in malignant hyperthermia

  • David Santiago Giraldo-Gutiérrez Anesthesiology Unit, Department of Surgery, Universidad Nacional de Colombia, Bogotá, Colombia.
  • Marco Andrés Arrendo-Verbel Anesthesiology Unit, Department of Surgery, Universidad Nacional de Colombia, Bogotá, Colombia.
  • David A. Rincón-Valenzuela Anesthesiology Unit, Department of Surgery, Universidad Nacional de Colombia, Bogotá, Colombia.
Keywords: Malignant Hyperthermia, Dantrolene, Education Continuing, Simulation Training

Abstract

Malignant hyperthermia is a potentially lethal condition triggered by succinylcholine exposure or exposure to halogenated anesthetic agents. Early identification of the crisis, as well as the timely administration of the specific treatment, impact the patient's outcomes. Any potential difficulties for dandrolene reconstitution are critical and may cause delays or preventable errors, if the operator is not familiar with the preparation and administration of the drug. The development of a simulation model to learn the process offers the possibility to acquire one of the skills required when facing a crisis of malignant hyperthermia. The high cost of the vials and sometimes the difficult access to the medication due to lack of availability in many institutions makes the option of simulating dantrolene reconstitution attractive, in order to familiarize the surgical team with the management of the drug. In this scenario, we submit a simulation model to learn the process of preparation of dandrolene in a controlled environment.

References

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How to Cite
1.
Giraldo-Gutiérrez DS, Arrendo-Verbel MA, Rincón-Valenzuela DA. Dantrolene reconstitution: description of a simulation model in malignant hyperthermia. Colomb. J. Anesthesiol. [Internet]. 2018 Apr. 1 [cited 2024 Mar. 28];46(2):152-8. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/216

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Published
2018-04-01
How to Cite
1.
Giraldo-Gutiérrez DS, Arrendo-Verbel MA, Rincón-Valenzuela DA. Dantrolene reconstitution: description of a simulation model in malignant hyperthermia. Colomb. J. Anesthesiol. [Internet]. 2018 Apr. 1 [cited 2024 Mar. 28];46(2):152-8. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/216
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