Sugammadex in the neonatal patient

  • Víctor Hugo González Cárdenas Anesthesiologist, Pontificia Universidad Javeriana; Clinical Epidemiologist, Universidad del Bosque; Professor FUCS, Hospital Infantil Universitario San José; Clinical Professor, Universidad de La Sabana; Anesthesiologist, Hospital Universitario Samaritana, Bogotá, Colombiac Research Group in Anesthesiologist «Deorum Opus» - Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia
  • Freddy Danilo Munar González Anesthesiologist, Universidad del Rosario; Professor FUCS, Hospital Infantil Universitario San José, Bogotá, Colombia c Research Group in Anesthesiologist «Deorum Opus» - Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, Colombia
Keywords: Infant, Newborn Neuromuscular blocking agents General, Anesthesia Neostigmine


lntroduction: The inclusion of drugs that effectively reverse the neuromuscular junction blockade enhances the profile of drugs used for relaxation of the neuromuscular junction; betteryet if these agents are free from any clinically important adverse effects and amenable to use in neonates.

Objectives: This article describes a case of two pediatric patients who received Sugammadex to reverse neuromuscular relaxation.

Methodology: Retrospective, descriptive, observational study designed as a case report. Results:This is a description of a Sugammadex successful reversal of Rocuronium-induced neuromuscular blockade in two neonates with no adverse events.

Discussion: The literature on the use of Sugammadex in newborn patients is scarce and controversial which does not contribute to a broad prescription of the drug in neonatology settings due to the shortage of studies attesting to its effectiveness and absence of adverse effects. There are no recommended doses per age group and a list of expected adverse effects to contraindicate its administration. However, the idea is to have available drugs that reverse the relaxation resulting from the use of neuromuscular blockers at any age, including neonates.

Conclusions: Following the administration of a dose of Sugammadex the reversal of neuromuscular blockade in neonate patients is described with effective functional recovery of the neuromuscular junction. Further experimental controlled trials are needed to recommend the use of Sugammadex in newborn babies.


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How to Cite
González Cárdenas VH, Munar González FD. Sugammadex in the neonatal patient. Colomb. J. Anesthesiol. [Internet]. 2013Apr.1 [cited 2022May20];41(2):171-4. Available from:


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How to Cite
González Cárdenas VH, Munar González FD. Sugammadex in the neonatal patient. Colomb. J. Anesthesiol. [Internet]. 2013Apr.1 [cited 2022May20];41(2):171-4. Available from:
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