Successful systemic fibrinolysis in a patient with Covid- 19: Case report

  • Beatriz Flores Cajal Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain. https://orcid.org/0000-0001-7505-1732
  • Begoña Ortolá Rocher Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain. https://orcid.org/0000-0002-7796-7792
  • Laura Betolaza Weimer Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Diego Gil Mayo Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain. https://orcid.org/0000-0002-2695-2224
  • María León Núñez Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Paloma Repáraz Grávalos Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • María Gómez Rojo Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Guillermo Bartolomé Rubio Anesthesia, Hospital Universitario Ramón y Cajal. Madrid, Spain.
Keywords: ARDS, COVID-19, Coagulopathy, Fibrinolysis, Pulmonary thromboembolism, SARS-Cov-2

Abstract

The new coronavirus 2019-nCov or SARS-Cov-2 is responsible for the most important pandemic in the 21st century: the coronavirus disease (COVID-19).

The 2019-nCov infection elicits a hyper-coagulable state, conditioning a worse outcome in these patients. The pathophysiology of the exaggerated coagulation activation in these patients is still unknown, and probably involves several mechanisms, different from those involved in sepsis-associated coagulopathy.

This article discusses the case of a patient with no remarkable medical history, who after 7 days of fever, diarrhea and epigastric pain was diagnosed with COVID-19 bilateral pneumonia, further aggravated by severe Acute Respiratory Distress Syndrome. In this context, the patient experienced a massive acute pulmonary thromboembolism accompanied by an acute thrombus in the heart’s right ventricle, leading to hemodynamic instability. For the first time in our center in these patients, systemic fibrinolysis was successfully performed, with resolution of the intracavitary thrombus and the acute hemodynamic shock.

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How to Cite
1.
Flores Cajal B, Ortolá Rocher B, Betolaza Weimer L, Gil Mayo D, León Núñez M, Repáraz Grávalos P, Gómez Rojo M, Bartolomé Rubio G. Successful systemic fibrinolysis in a patient with Covid- 19: Case report. Colomb. J. Anesthesiol. [Internet]. 2021Mar.9 [cited 2021Jul.28];49(3). Available from: https://www.revcolanest.com.co/index.php/rca/article/view/969

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Published
2021-03-09
How to Cite
1.
Flores Cajal B, Ortolá Rocher B, Betolaza Weimer L, Gil Mayo D, León Núñez M, Repáraz Grávalos P, Gómez Rojo M, Bartolomé Rubio G. Successful systemic fibrinolysis in a patient with Covid- 19: Case report. Colomb. J. Anesthesiol. [Internet]. 2021Mar.9 [cited 2021Jul.28];49(3). Available from: https://www.revcolanest.com.co/index.php/rca/article/view/969
Section
Case Report / Case Series

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