Protocol and importance of using the kit for local anesthetic systemic toxicity

  • Marta Inés Berno Valencia Hospital Pablo Tobón Uribe, Medellín, Colombia
  • Juan Felipe Vargas Silva Hospital Pablo Tobón Uribe, Medellín, Colombia
Keywords: Anesthetics Local, Toxicity, Lipids, Anesthesia, Conduction, Operating, Rooms


Systemic toxicity due to local anesthetics is one of the most feared complications in regional anesthesia due to the risk for the heart, the central nervous system and, in particular, the risk of triggering cardiorespiratory arrest, which is difficult to manage, even in healthy patients. Prevention as the main goal, together with prompt recognition and early treatment using several general measures followed by specific treatment with 20% lipid emulsions, improve prognosis dramatically for these patients. Their immediate availability in the operating theater or in areas where regional anesthesia is provided such as the emergency services and rooms where blocks are performed, may make the difference between a favorable or adverse prognosis in situations of severe systemic toxicity from local anesthetics.

The objective of this article is to create awareness on the prevention of toxicity events due to local anesthetics and provide knowledge about the management protocols in case such events should happen, recognizing the importance of having a toxicity kit available during daily practice and of following basic management guidelines adapted to the needs of each institution because, although this is a rare occurrence, it may be devastating.


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How to Cite
Berno Valencia MI, Vargas Silva JF. Protocol and importance of using the kit for local anesthetic systemic toxicity. Colomb. J. Anesthesiol. [Internet]. 2013Oct.1 [cited 2022Aug.14];41(4):274 -279. Available from:


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How to Cite
Berno Valencia MI, Vargas Silva JF. Protocol and importance of using the kit for local anesthetic systemic toxicity. Colomb. J. Anesthesiol. [Internet]. 2013Oct.1 [cited 2022Aug.14];41(4):274 -279. Available from:
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