Comparison of emergence and discharge times between two Total Intravenous Anesthesia techniques: Remifentanil and Fentanyl
Introduction: Despite the widespread use of Propofol-opioid combinations for induction and maintenance of adequate anesthesia and analgesia, there are no studies comparing the use of manual Total Intravenous Anesthesia with Remifentanil-Propofol versus Fentanyl-Propofol.
Objective: To compare emergence and discharge times between two Total Intravenous Techniques used at Occidente de Kennedy Hospital, one based on Propofol and Remifentanil (manual infusion) and the other based on Stangraf-controlled Propofol and Fentanyl.
Method: Analytical observational study for the comparison of two groups of subjects, one exposed to Remifentanil plus Propofol and the other exposed to Fentanyl plus Propofol, comprising 43 patients taken to surgery under Total Intravenous Anesthesia at Occidente de Kennedy Hospital. Data were analyzed using the Shapiro-Wilks, Student t and Mann-Whitney U tests and the Spearman and Pearson correlation coefficients, using Windows SPSS, version 20. A p value <0.05 was accepted as statistically significant.
Results: In comparing the two techniques, no statistically significant time differences were found. The mean emergence time was 10.1 min for Fentanyl and 10.2 min for Remifentanil. The discharge time for Fentanyl was 11.9 min and 11.5 min for Remifentanil.
Conclusions: The Stangraf-guided use of Fentanyl-Propofol combination is equivalent to the use of Remifentanil-Propofol (manual infusion) in terms of emergence and discharge times. Additional studies are required in order to confirm these findings.
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