From pharmacokinetics to pharmacodynamics -Are we ready for 3D software?

  • Luis Alberto Tafur-Betancourt SEGANEST, Clinica Visual y Auditiva Instituto para niños ciegos y sordos del Valle del Cauca, Cali, Colombia
  • F. Eduardo Lema Hospital Universitario del Valle "Evaristo García”, Cali, Colombia
  • G. Maria Del Mar-Milla Universidad Libre, Cali Campas, Cali, Colombia
  • Alejandro Londoño DESA Clinic, Cali, Colombia
  • José Ricardo Navarro-Vargas a. School of Medicine, Universidad Nacional de Colombia, Bogotá, D.C., Colombia. b. President Colombian Society of Anesthesiology and Resuscitation - S.C.A.R.E., Bogotá, D.C., Colombia
Keywords: Anesthesia, Balanced anesthesia, Pharmacology, Pharmacokinetics, Software, Intravenous

Abstract

The relationship between the dose and plasma concentration of a drug is determined by pharmacokinetics. However, difficulties arise when more than one drug is administered simultaneously. There is currently a gap in the teaching model when trying to convey the significance of pharmacodynamic interactions. In this article the authors reflect on the importance of developing a software that simplifies the pharmacokinetic concepts of two drugs, turning them into one single variable in space as a function of time. Together with depth of anesthesia monitoring and the pain control variables, this model will bring pharmacokinetics and pharmacodynamics together and provide a teaching tool for improved understanding of these concepts.

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How to Cite
1.
Tafur-Betancourt LA, Lema FE, Del Mar-Milla GM, Londoño A, Navarro-Vargas JR. From pharmacokinetics to pharmacodynamics -Are we ready for 3D software?. Colomb. J. Anesthesiol. [Internet]. 2017Oct.1 [cited 2021Jun.24];45(4):335–339. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/562

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Published
2017-10-01
How to Cite
1.
Tafur-Betancourt LA, Lema FE, Del Mar-Milla GM, Londoño A, Navarro-Vargas JR. From pharmacokinetics to pharmacodynamics -Are we ready for 3D software?. Colomb. J. Anesthesiol. [Internet]. 2017Oct.1 [cited 2021Jun.24];45(4):335–339. Available from: https://www.revcolanest.com.co/index.php/rca/article/view/562
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Essay

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