The hidden world of drug interactions in anesthesia☆

  • Luis Alberto Tafur-Betancourt SEGANEST, Clínica Visual y Auditiva, Instituto para niños ciegos y sordos del Valle del Cauca, Cali, Colombia.
Keywords: Pharmacology, Drug Interactions, Chemistry, pharmaceutical, Pharmacokinetics, Anesthesia


Drug interactions represent the cornerstone in the basic anesthetic triangle and knowledge about such interactions contributes to a solid foundation for administering medications.

This article dwells on the anesthetic drug interactions: pharmaceutical (mixing or not mixing), pharmacokinetic (alterations in distribution, metabolism, or clearance), pharmacodynamics (synergism, additive effect) and thermodynamic (affinity and intrinsic activity).

The basic anesthetic triangle is a current concept and drug interactions are the cornerstone for safe anesthesia. These interactions are currently neglected and hence the anesthetist should recognize any drug interactions for a safer practice of anesthesia.


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How to Cite
Tafur-Betancourt LA. The hidden world of drug interactions in anesthesia☆. Colomb. J. Anesthesiol. [Internet]. 2017Jul.1 [cited 2022Jul.6];45(3):216–223. Available from:


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How to Cite
Tafur-Betancourt LA. The hidden world of drug interactions in anesthesia☆. Colomb. J. Anesthesiol. [Internet]. 2017Jul.1 [cited 2022Jul.6];45(3):216–223. Available from:

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